Health Testing


What is DNA (Genetic) testing?
Have you ever seen a dog that is blind? In most cases, they are a victim of PRCD, which could have been prevented. A DNA test is a test that looks for certain diseases (like PRCD, and others) in your dog’s DNA. There are a few diseases that can affect AussieDoodles, and of both mom and dad could be carriers of that disease, or worse yet, affected by it, meaning they will suffer from it.

What would happen if a puppy was affected?
Lets say for example, a puppy is affected by PRCD. There is a very high chance this puppy will go blind between the ages of 3 and 7 years old.

How do you prevent a puppy from being affected?
The only way to ensure puppies cannot be affected by a disease like PRCD, is to test both mom and dad. Mom and dad test results could be as follows:
Clear
Carrier
Double carrier (affected)

Lets suppose a breeder didn’t test their dogs, because they thought they were fine: “My dogs are 5 years old and they can see fine, there is no reason to test.” However, what they don’t understand that is that dogs can be “carriers”. If mommy OR daddy is a carrier, it’s no problem. The problem can happen when both mom and dad are carriers.

Here are the possible outcomes:
Neither parent is a carrier = clear puppy
One parent is a carrier, and the other is not = 50% chance a puppy will be a carrier (still OK)
Both parents are carriers = 25% chance puppy will be a double carrier, affected (will go blind)
One parent is a double carrier, other clear = 50% chance puppy will be affected
One parent is a double carrier, other is carrier = 75% chance puppy will be affected

How does AwesomeDoodle test their dogs?
We use a swab to collect DNA from every mommy or daddy dog. These swabs are sent off to pawprint genetics. They give us results within 2 weeks to let us know. If any dog is a double carrier, they are not authorized to make puppies. If one parent is a carrier, we are sure to mate it with a non carrier.

Here’s how we do it.

 

For our poodles, we test for:

Degenerative Myelopathy
Aliases: Canine degenerative myelopathy, DM

GM2 Gangliosidosis (Poodle Type)
Aliases: Sandhoff disease, Type 0 gangliosidosis

Osteochondrodysplasia
Aliases: Skeletal dwarfism, OCD

Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Aliases: PRA-PRCD, PRCD

Von Willebrand Disease I
Aliases: Pseudohemophilia, Vascular hemophilia, von Willebrand disease type 1, von Willebrand’s disease, VWDI

 

 

For our Aussies, we test for:

Collie Eye Anomaly
Aliases: Choroidal hypoplasia, CEA, CH

Cone Degeneration
Aliases: Achromatopsia, Day blindness, Hemeralopia, Rod monochromacy, CD

Degenerative Myelopathy
Aliases: Canine degenerative myelopathy, DM

Hereditary Cataracts (Australian Shepherd Type)
Aliases: Early onset cataracts, Juvenile cataracts, HC, HSF4, JC

Hyperuricosuria
Aliases: Urolithiasis, HUU

Multidrug Resistance 1
Aliases: Ivermectin sensitivity, MDR1 gene defect, Multidrug sensitivity, MDR1

Multifocal Retinopathy 1
Aliases: Canine multifocal retinopathy 1, CMR1

Neuronal Ceroid Lipofuscinosis 6
Aliases: Amaurotic idiocy, Batten disease, NCL, NCL6

Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Aliases: PRA-PRCD, PRCD

OFA testing (Orthepedic Foundation for Animals)
We do this with all our dogs once they are over 2 years old. This process involves getting our dog’s hips and legs x-rayed and then those x-rays are sent off to OFA. OFA then analyzes the x-rays and they give us a rating on our dog’s hips and joints.